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Population pharmacokinetics and dosing of amoxicillin in (Pre. corrected for body weight (CL/W) was 0.096 ± 0.036 L kg-1 h-1, mean elimination half-life (t.1/2 elimination half-life, PAE significant post-antibiotic effect >2 h where known (no or. Amoxicillin (419) T N 18 0.21 10 60 Cefotaxime (477) T N 38 0.3 40 60.<